Cart
sales@molnova.com
KN-92 hydrochloride
CAS No. 1431698-47-3
KN-92 hydrochloride( —— )
Catalog No. M22113 CAS No. 1431698-47-3
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 82 | In Stock |
|
| 5MG | 164 | In Stock |
|
| 10MG | 246 | In Stock |
|
| 25MG | 447 | In Stock |
|
| 50MG | 651 | In Stock |
|
| 100MG | 888 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameKN-92 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionKN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
-
DescriptionKN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetCaMK
-
RecptorCaMKII
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1431698-47-3
-
Formula Weight493.45
-
Molecular FormulaC24H26Cl2N2O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:40 mg/mL (81.06 mM)
-
SMILESCl.COc1ccc(cc1)S(=O)(=O)Nc1ccccc1CN(C)C\C=C\c1ccc(Cl)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Rezazadeh S, Claydon TW, Fedida D. et al. KN-93 (2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine), a calcium/calmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. J Pharmacol Exp Ther. 2006 Apr;317(1):292-9.
molnova catalog
related products
-
Perphenazine
Perphenazine is a typical antipsychotic drug, inhibits 5-HT2A receptor (5-HT2A), Alpha-1A adrenergic receptor (α1A), Dopamine receptor D2/D3, D2L receptor, and Histamine H1 receptor (H1).
-
W-9 hydrochloride
W-9 hydrochloride is a calmodulin antagonist.
-
SCR7 pyrazine
SCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ).
